Peroxisome Proliferator- Activated Receptors (PPARs): A Review on Effects on Glucose Metabolism, Energy Homeostasis and Cardiovascular System

نویسندگان

چکیده

Background:Molecular biology and human medical genetics have introduced several novel biomarkers giving control over vital body functions, of these are transcriptional factors known as peroxisome proliferator activated- receptors “PPARs”. The aim this review is to shed light on available online information published research works about biomarkers. current will try display those findings mainly related energy homeostasis, glucose metabolism, insulin sensitivity some cardiovascular interactions. Methods:a literature their roles in controlling functions has been made recorded. Search covered investigations the last three decades accessible. Results: crucial a big deal biological processes humans. Conclusions: Peroxisome proliferator-activated important with clinical impacts. Literature shows wide spectrum effects interactions through affecting many genes involved balance, peripheral sensitization addition interfering inflammation, angiogenesis, blood pressure atherosclerosis.

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ژورنال

عنوان ژورنال: Annals of the College of Medecine

سال: 2022

ISSN: ['2309-6217', '0027-1446']

DOI: https://doi.org/10.33899/mmed.2022.133951.1148